abstract：BACKGROUND:Despite some improvements in dialysis therapies, depression still remains an important problem in chronic hemodialysis (HD) patients. In this study, we aimed to investigate the association of depression and its treatment with quality of life (QOL) in HD patients. PATIENTS AND METHODS:97 HD patients (52 male...

journal_title：Clinical nephrology

authors： Turk S,Atalay H,Altintepe L,Güney I,Okudan N,Tonbul HZ,Gökbel H,Kücür R,Yeksan M,Yildiz A

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Several types of replacement fluid and methods of anticoagulation have been employed for continuous renal replacement therapy, but there is no consensus on a preferred approach. We evaluated the indications for the selection of replacement fluid and anticoagulant among critically ill patients receiving conti...

journal_title：Clinical nephrology

authors： Palsson R,Laliberte KA,Niles JL

更新日期：2006-01-01 00:00:00

abstract：:The pathomechanism of the ANCA-associated vasculitides is discussed in light of the abstracts presented at the ANCA- and Vasculitis Workshop 2005 in Heidelberg! ...

journal_title：Clinical nephrology

authors： Hänsch GM,Iking-Konert C,Andrassy K

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The histology and function of the kidney deteriorates with age and progressive renal failure, but the mechanisms involved in renal ageing are not known. In vitro studies suggest that telomere shortening is important in replicative senescence, and is accelerated by stress factors that increase replication. We...

journal_title：Clinical nephrology

authors： Szeto CC,Poon PY,Lai FM,Chow KM,Szeto CY,Li PK

更新日期：2005-11-01 00:00:00

abstract：AIMS:An increasing amount of evidence suggests that 25-hydroxy vitamin D3 (25(OH)D3) may contribute to the bone health of patients with chronic kidney disease (CKD). The underlying vitamin D status of these patients, however, has often been neglected. In a cross-sectional study we assessed the association between vitam...

journal_title：Clinical nephrology

authors： Mucsi I,Almási C,Deák G,Marton A,Ambrus C,Berta K,Lakatos P,Szabó A,Horváth C

更新日期：2005-10-01 00:00:00

abstract：:A 48-year-old Japanese woman previously in good health was found to have severe proximal tubular dysfunction with a high serum level of ascorbic acid (57.3 microg/ml, reference range: 1.9 - 15.0 microg/ml). Renal biopsy specimen showed marked tubulointerstitial damage, i.e. tubular atrophy, dilatation of tubular lumen...

journal_title：Clinical nephrology

authors： Ohtake T,Kobayashi S,Negishi K,Moriya H

更新日期：2005-09-01 00:00:00

abstract：AIM:Studies haveshown lower infection rates of port systems compared to established, transcutaneous cuffed-tunneled dialysis catheters. This was shown in otherwise quite healthy patients starting hemodialysis treatment. It is unclear to what extent these results can be applied to countries such as Germany where, unlike...

journal_title：Clinical nephrology

authors： Hollenbeck M,Zolotov D,Debusmann ER,Koch M,Wozniak G

更新日期：2005-08-01 00:00:00

abstract：AIMS:Adiponectin seems to be an important modulator for metabolic and vascular diseases. We aimed to measure plasma adiponectin levels in type 2 diabetic patients and investigate any association with the severity of proteinuria. METHODS:80 patients (mean age, 46.9 +/- 5.1 years; body mass index (BMI), 25.8 +/- 1.98 kg...

journal_title：Clinical nephrology

authors： Yenicesu M,Yilmaz MI,Caglar K,Sonmez A,Eyileten T,Kir T,Acikel C,Bingol N,Oguz Y,Ikizler TA,Vural A

更新日期：2005-07-01 00:00:00

abstract：:An 8-year-old girl with preexisting chronic renal failure (CRF) due to bilateral renal hypoplasia presented with edema, gross hematuria and acute deterioration of renal function. The diagnosis of poststreptococcal acute glomerulonephritis (PSAGN) was made based on clinical presentation, red blood cell casts, low level...

journal_title：Clinical nephrology

authors： Naito-Yoshida Y,Hida M,Maruyama Y,Hori N,Awazu M

更新日期：2005-06-01 00:00:00

abstract：:A 16-year-old Japanese girl was admitted to our hospital on February 27, 2001, for acute renal failure. She had not shown proteinuria or hematuria in any school examination through 2000. The first renal biopsy specimen showed focal segmental glomerulosclerosis and tubulointerstitial change. Electron microscopy showed ...

journal_title：Clinical nephrology

authors： Chinen S,Tana T,Kohagura K,Yamazato M,Iseki K,Takishita S

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Hyperlipidemia may develop early in the course of renal disease, and statin treatment to lower lipid levels in these patients is effective. In addition, it has been suggested that proteinuria may decrease after prolonged periods of statin treatment. In the present study, we set out to evaluate the short-term...

journal_title：Clinical nephrology

authors： Ozsoy RC,Koopman MG,Kastelein JJ,Arisz L

更新日期：2005-04-01 00:00:00

abstract：:Hepatic portal venous gas (HPVG) has been rarely described in chronic hemodialysis patients. We report a case of HPVG in a 59-year-old female patient with hemodialysis-dependent chronic renal failure due to diabetes who presented with acute onset of abdominal pain. Abdominal CT demonstrated the presence of gas in the ...

journal_title：Clinical nephrology

authors： Iguchi S,Alchi B,Safar F,Kasai A,Suzuki K,Kihara H,Hirota M,Nishi S,Gejyo F,Ohno Y

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Various immunological and non-immunological pathomechanisms are responsible for the cellular damage in renal allografts. Since the kidney is an anatomically complex organ with functional and morphological heterogeneous compartments (interstitium, tubuli, vessels, glomeruli), the local response to injury mayb...

journal_title：Clinical nephrology

authors： Serinsöz E,Bock O,Kirsch T,Haller H,Lehmann U,Kreipe H,Mengel M

更新日期：2005-03-01 00:00:00

abstract：AIMS:Recombinant human erythropoietin (r-HuEPO) is widely used to correct renal anemia in uremic patients. Interestingly, some chronic hemodialysis (HD) patients can maintain high hemoglobin level without the need of r-HuEPO. The aim of this study is to investigate clinical features, iron metabolism and erythropoiesis ...

journal_title：Clinical nephrology

authors： Kuo CC,Lee CT,Chuang CH,Su Y,Chen JB

更新日期：2005-02-01 00:00:00

abstract：:We describe a case of 51-year-old male with fever, abdominal pain and inguino-scrotal hernia. Laboratory examination revealed hypercreatininemia and hyperglycemia, firstly interpreted as diabetic nephropathy. US and CT scan showed a hernia of the bladder into the scrotum. Surgery revealed multiple bladder perforations...

journal_title：Clinical nephrology

authors： Manna R,Mirk P,Sallustio G,Brisinda G,Izzi D,La Regina M,Nucera G,Maria G,Montalto M,Ghirlanda G

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:alpha1-antitrypsin (AAT) is the main protease inhibitor in the blood. Several different AAT phenotypes exist. The most common variant is the MM phenotype, which is also associated with normal AAT levels. The less common phenotypes with Z and S variants are associated with low AAT levels. AAT deficiency is a ...

journal_title：Clinical nephrology

authors： Szönyi L,Dobos M,Vásárhelyi B,Héninger E,Vas T,Nagy J,Kovács T

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Hemodialysis patients (HD) are exposed to oxidative stress which contributes to cardiovascular disease and accelerated atherosclerosis, major causes of mortality in these patients. A new dialysis membrane coated with vitamin E has been proposed against oxidative stress and atherosclerosis due to their abilit...

journal_title：Clinical nephrology

authors： Calò LA,Naso A,Pagnin E,Davis PA,Castoro M,Corradin R,Riegler P,Cascone C,Huber W,Piccoli A

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Increased blood levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) predict cardiovascular mortality in patients with end-stage renal disease. Despite its low molecular weight, available information on the impact of hemodialysis (HD) on ADMA plasma levels is controvers...

journal_title：Clinical nephrology

authors： Kielstein JT,Böger RH,Bode-Böger SM,Martens-Lobenhoffer J,Lonnemann G,Frölich JC,Haller H,Fliser D

更新日期：2004-10-01 00:00:00

abstract：AIMS:To evaluate the influence of sepsis in critically ill patients with acute renal failure (ARF), and to analyze the value of the sequential organ failure assessment (SOFA) score for assessing the morbidity and related mortality of these patients. MATERIAL AND METHODS:A prospective observational study developed in a...

journal_title：Clinical nephrology

authors： Carbonell N,Blasco M,Ferreres J,Blanquer J,García-Ramón R,Mesejo A,Miguel A

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:It is well-known that hemodialysis patients experience increased oxidative stress, which is believed to cause numerous uremia-related complications. Retention of water-soluble toxins as well as protein-bound toxins is due to renal failure. Kidney transplantation restores, at least partially, the fundamental ...

journal_title：Clinical nephrology

authors： Antolini F,Valente F,Ricciardi D,Fagugli RM

更新日期：2004-08-01 00:00:00

abstract：AIM:Hemodialysis for patients bleeding or at risk for bleeding requires special modalities of treatment that are difficult to perform without potential side effects. A simple, safe and adequate method may be applied. METHODS:A modified way of extracorporeal circuit preparation, which focuses on minimizing the blood-ai...

journal_title：Clinical nephrology

authors： Stamatiadis DN,Helioti H,Mansour M,Pappas M,Bokos JG,Stathakis CP

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Oxidative stress is implicated in the pathogenesis of chronic kidney disease (CKD) and essential hypertension (EHTN). However, the role of hypertension in causing increased oxidative stress in patients with CKD is unknown. METHODS:We performed a case control study in patients with EHTN and those with equal ...

journal_title：Clinical nephrology

authors： Agarwal R

更新日期：2004-06-01 00:00:00

abstract：:A case of severe acute renal failure in a young female patient necessitating renal replacement therapy after laparoscopic cholecystectomy is described. The histology of the renal lesion assigned to the effects of laparoscopic surgery is relevant for the pathogenesis of renal complications after such procedures. This e...

journal_title：Clinical nephrology

authors： Apostolou T,Sotsiou F,Dimitriades G,Nikolopoulou N,Chilal K,Balanika M,Yiannopoulos P,Hadjiconstantinou V

更新日期：2004-06-01 00:00:00

abstract：:Health-related quality of life (HRQoL) consists of a number of components like functional status, psychological and social functioning, cognition and disease and treatment-related symptoms. End-stage renal disease (ESRD) patients display emotional disturbances, as well as non-adherence to treatment and fluid and food ...

journal_title：Clinical nephrology

authors： Kouidi E

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Chronic hepatitis C virus (HCV) infection is a common infectious agent in chronic hemodialysis (HD) patients. In this prospective case-control study, we aimed to investigate the influence of chronic HCV infection on erythropoietin (EPO) and iron requirement in HD patients. PATIENTS AND METHODS:49 HD patient...

journal_title：Clinical nephrology

authors： Altintepe L,Kurtoglu E,Tonbul Z,Yeksan M,Yildiz A,Türk S

更新日期：2004-05-01 00:00:00

abstract：:This prospective study examines 42 children in the first year after renal transplantation. They all received intravenous ganciclovir prophylaxis for cytomegalovirus in the immediate post-transplant period. Quantitative antigenemia (pp68) determinations and blood, urine and throat cultures were done on a scheduled basi...

journal_title：Clinical nephrology

authors： Melgosa Hijosa M,García Meseguer C,Peña Garcia P,Alonso Melgar A,Espinosa Román L,Peña Carrión A,Navarro Torres M

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:[corrected] Advanced glycation end products (AGEs), total homocysteine (tHcy) and the homocysteine metabolites cystathionine (Cysta) and dimethylglycine (DMG) are increased in serum of patients with end-stage renal disease. The aim of this prospective randomized study was to compare the efficacy of polysulfo...

journal_title：Clinical nephrology

authors： Klemm A,Franke C,Busch M,Müller A,Franke S,Lang D,Passlick-Deetjen J,Stein G

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Mortality rates of cirrhotic patients with renal failure admitted to the medical intensive care unit (ICU) are high. End-stage liver disease is frequently complicated by disturbances of renal function. This investigation is aimed to compare the predicting ability of acute physiology, age, chronic health eval...

journal_title：Clinical nephrology

authors： Chen YC,Tsai MH,Ho YP,Hsu CW,Lin HH,Fang JT,Huang CC,Chen PC

更新日期：2004-02-01 00:00:00

abstract：:Few cases of pamidronate (bisphosphonate class of drugs) nephrotoxicity in humans have been previously reported in the literature. In 7 patients, the pamidronate-related nephrotoxicity was attributed to focal collapsing glomerulosclerosis [Markowitz et al. 2001], and in 1 patient was related to tubulo-interstitial inf...

journal_title：Clinical nephrology

authors： Smetana S,Michlin A,Rosenman E,Biro A,Boaz M,Katzir Z

更新日期：2004-01-01 00:00:00

abstract：:We report a case of a woman with a poorly functioning renal allograft and a positive anti-cardiolipin antibody who was dialysis-independent and conceived 18 months following her transplant. She was electively maintained on hemodialysis during the pregnancy and delivered a live infant at 31 weeks gestation. Her renal f...

journal_title：Clinical nephrology

authors： Al-Jayyousi R,Carr S,Hodgett S,Scudamore I,Howarth E,Singlehurst A,Brunskill N

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) have significant impairments in health-related quality of life (HRQOL). In part, this is due to the intrusiveness of the treatment (hemodialysis or peritoneal dialysis) that is required. It is unclear whether hemodialysis or peritoneal dialysis is associated with ...

journal_title：Clinical nephrology

authors： Manns B,Johnson JA,Taub K,Mortis G,Ghali WA,Donaldson C

更新日期：2003-11-01 00:00:00

abstract：:Patients with diabetic nephropathy have an increased risk of coronary heart disease (CHD). Paraoxonase (Pon1) is a high-density lipoprotein- (HDL) associated enzyme that protects low-density lipoprotein from oxidation and also protects against atherosclerosis. We investigated the relationship of serum Pon1 activity, P...

journal_title：Clinical nephrology

authors： Zhang B,Eto S,Fan P,Bian C,Shimoji E,Saito T,Saku K

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Radiocontrast medium- (RM) associated nephrotoxicity continues to be a common cause of acute renal failure and may lead in patients with pre-existing chronic renal insufficiency even to end-stage renal failure requiring chronic dialysis. Since extracorporeal removal of RM after RM administration has been sho...

journal_title：Clinical nephrology

authors： Frank H,Werner D,Lorusso V,Klinghammer L,Daniel WG,Kunzendorf U,Ludwig J

更新日期：2003-09-01 00:00:00

abstract：AIMS:We evaluated the benefits and safety of nateglinide, a novel oral hypoglycemic agent, in type 2 diabetes patients with renal failure. METHODS:Single-dose pharmacokinetics were studied in 8 patients with type 2 diabetes and a low creatinine clearance (range 1.8-16.5 ml/min/1.73 m2) up to 6 hours after 90 mg nategl...

journal_title：Clinical nephrology

authors： Inoue T,Shibahara N,Miyagawa K,Itahana R,Izumi M,Nakanishi T,Takamitsu Y

更新日期：2003-08-01 00:00:00

abstract：:Cardiovascular complications are a major clinical problem in patients with chronic kidney disease and end stage renal failure. Death from cardiac causes accounts for 40%-50% of all deaths in these patients and is thus up to 20 times more common in uremic patients than in the general population. Cardiovascular patholog...

journal_title：Clinical nephrology

authors： Amann K,Tyralla K,Gross ML,Eifert T,Adamczak M,Ritz E

更新日期：2003-07-01 00:00:00

abstract：:Chronic heart failure (CHF) is an important public health care problem and a leading cause of morbidity and mortality world wide. Anemia is a common finding in CHF and known to cause heart failure. Patients with CHF are limited by exercise capacity and fatigue. A low hemoglobin concentration leads to impairment of bot...

journal_title：Clinical nephrology

authors： Steinborn W,Doehner W,Anker SD

更新日期：2003-07-01 00:00:00

abstract：AIM:Human immune response can be classified into 2 different subsets of T helper cells (Th1 and Th2) based on the pattern of cytokine production. In modern immunology, Th1/Th2 paradigm helps to explain the different inflammatory effector pathways and outcomes in human diseases. The present study was designed to determi...

journal_title：Clinical nephrology

authors： Masutani K,Tokumoto M,Nakashima H,Tsuruya K,Kashiwagi M,Kudoh Y,Fukuda K,Kanai H,Akahoshi M,Otsuka T,Hirakata H,Iida M

更新日期：2003-06-01 00:00:00

abstract：:Calcific uremic arteriolopathy (calciphylaxis) is one of the more devastating complications that can develop in patients with chronic renal failure. This disorder is associated with calcium-phosphorus deposition in the subcutaneous arterial vessels and presents as a progressive ischemic necrosis of the skin resulting ...

journal_title：Clinical nephrology

authors： Don BR,Chin AI

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Hemodialysis patients very often suffer from malnutrition with net loss of body muscle and fat stores. Since protein-calorie malnutrition has been considered to be highly associated with increased morbidity and mortality, it is important that the nutritional status is evaluated accurately and that long-term ...

journal_title：Clinical nephrology

authors： Takahashi N,Yuasa S,Fukunaga M,Hara T,Moriwaki K,Shokoji T,Hitomi H,Fujioka H,Kiyomoto H,Aki Y,Hirohata M,Mizushige K,Kohno M

更新日期：2003-05-01 00:00:00

abstract：AIM:To study the efficacy and safety of tacrolimus in primary membranous nephropathy. METHOD:We describe 3 patients with primary membranous nephropathy who were either resistant to or could not tolerate steroid with or without cytotoxic agents. They were treated with tacrolimus 0.2 mg/kg/day for 6 months. The dosage o...

journal_title：Clinical nephrology

authors： Szeto CC,Leung CB,Lai FM,Li PK

更新日期：2003-04-01 00:00:00